Exploring the potential of algae-bacteria interactions in the biocontrol of the marine pathogen Vibrio parahaemolyticus

Abstract The marine bacterium Vibrio parahaemolyticus is the leading cause of seafood-related food poisoning worldwide and a pathogen species harvested in aquaculture. An outbreak pathogenic V. within crustacean bi-valve aquaculture facilities often results significant loss farmed product spread into human population. Evidence shows several bacteria microalgae have antibacterial effects against pathogens, including . This study explored potential combining possible mutualistic as consortium to enhance properties Marine were screened with aim identifying those able successfully coexist while demonstrating growth suppression multiple strains. trial involved four screening phases find effective inhibitor gain insight species-specific influences on cell growth. combination Tetraselmis sp. Pseudoalteromonas peptidolytica achieved greatest inhibition rate all combinations. pairing resulted reduction up 24 ± 15% copy number mL −1 day two five examined strains days, compared control cultures absent probiotic bacteria. Applying consortia such this has for use biocontrol technique mariculture, but it will require additional research self-sustainability successful natural aquatic conditions.